Nandrolone Phenylpropionate
Durabol 100 is one of the brand names among numerous names of Deca Durabolin, which is actually the most popular brand name for the component Nandrolone Decanoate. Nandrolone is itself a DHT derived steroid, which has been attached to decanoate ester. The attachment increases the time for Nandrolone Decanoate to stay in the body. For the record, the prime component for Durabol 100, Nandrolone Decanoate was introduced in the medical field in 1962.
Uses
Anemia and chronic kidney diseases are to be treated by Durabol 100 in the USA. With that patients having issues with kidney failure, aplastic anemia, osteoporosis and inoperable breast cancer contractions can also be treated or supported with Durabol 100. The component has bioavailability through intramuscular dosages. The bioavailability percentage stands at 53 to 73%. This drug can also enrich the lean muscle mass in the body suffering from muscle wasting disorders or consequences from HIV AIDS or cancer.
Pharmacodynamics
As a relative to testosterone, Durabol 100 contains anabolic and androgenic potency ratios as 3.29-4.92 and 0.31 to 0.41, which appears to be higher than the testosterone. Nandrolone compounds have the highest ratio of testosterone potency that stands at 10:1. This compound is also maintains an usual norm of transformation for AAS with 5-alpha reductase to more potent AR agonist as it is found in DHT components. 5-Alpha reductase transforms into low-affinity 5-alpha dihydronandrolone in hair follicles, prostate gland, liver, and brain tissues. This actually contributes to prostate enlargement and hair fall at times due to Nandrolone-ester induced side effect.
Pharmacokinetics
Durabol 100 is consumed through intramuscular dosages and its metabolism works in the blood streams through hydrolysis and in the liver. The metabolites used in the component are – Nandrolone, 5-alpha Dihydronandrolone, 19-Norandrosterone, 19-Noretiocholanolone and various conjugates. Elimination half-life of the component spans for 6 to 12 days as intramuscular dosages. On the other hand, the steroid Nandrolone maintains a half-life of about 4.3 hours. The duration of the action sustains until 2 to 3 weeks. Like many other steroid dosage, it is also excreted by urine.
This steroid component has an androgen ester, which makes it capable to deal with Progestogen. This may signify aromatization due to overdoses.
Dosages
The dosages of Durabol 100 can be counted as 25 to 50mg once in every 6 to 12 weeks. This will make 2 to 8mg per week as intramuscular injection. 50mg once in every 2 to 4 weeks as intramuscular injection provides proper treatment for postmenstrual osteoporosis and inoperative breast cancer. The medical practitioners should oversee the treatments for kids, where their chronic kidney disease may require 25 to 50mg intramuscular injection. The intramuscular injections are available in oil formations.
Contradictions
Pregnancy, breastfeeding moms, male breast cancer patients, women having hypercalcemia issues, hypersensitivity on Nandrolone should refrain from consuming Durabol 100. Androgenic and estrogenic side effects should be observed in regard to prevent any sort of adverse reaction. People with hepatic conditions, troubled billrubin excretion due to liver problems should avoid using Durabol 100. Effects of virilization should be observed upon allowing the dosages of Durabol 100 on women.
FDA has considered this drug as a Schedule III drug with high liver toxicity potential. That is why it should be consumed under expert’s surveillance.
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